منابع مشابه
Dmd052597 1867..1874
The primary objective of this study was to determine the in vivo absorption properties of valacyclovir, including the potential for saturable proton-coupled oligopeptide transporter 1 (PepT1)-mediated intestinal uptake, after escalating oral doses of prodrug within the clinical dose range. A secondary aim was to characterize the role of PepT1 on the tissue distribution of its active metabolite,...
متن کاملCentennial Perspective
The publications by Peter B. Dews of a series of five articles entitled “Studies on Behavior”, beginning in 1955 and ending in 1959, were contributions of extraordinary significance in laying a foundation for the emergence of the discipline of behavioral pharmacology. The series of articles were rigorous in their approach, dramatic in terms of the results, and provocative in their implications....
متن کاملDmd059089 1867..1872
Monoclonal antibodies (mAbs) represent an important class of therapeutic modalities. To optimize their pharmaceutical properties, studies have focused on improving mAb pharmacokinetic/ pharmacodynamic profiles by modulating their interactions with the neonatal Fc receptor (FcRn). The influence of both the chemical and physical properties of IgGs has been examined in the context of FcRn interact...
متن کاملThe 1867 Virgin Island Tsunami
The 1867 Virgin Island Tsunami reached large magnitude on the coasts of the Caribbean Islands. A maximum tsunami height of 10 m was reported for two coastal locations (Deshaies and Sainte-Rose) in Guadeloupe. Modelling of the 1867 tsunami is performed in the framework of the nonlinear shallow-water theory. The directivity of the tsunami wave source in the Caribbean Sea according to the assumed ...
متن کاملLithotomy versus Lithotrity in 1867
inquiry as to the methods used by Indian Surgeons in doing lithotomy, and their experience of lithotrity. In this way he collected statistics of 1,585 cases of lithotomy at different ages with an average mortality of 1 in 6. It is stated that in the opinion of many Surgeons in India " lithotomy will, in all probability, never be supplanted by lithotrity." This opinion was based upon the followi...
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ژورنال
عنوان ژورنال: ARCTIC
سال: 1967
ISSN: 1923-1245,0004-0843
DOI: 10.14430/arctic3283